GLP‑1 injection sites and how to rotate them.
The US labels for injectable GLP‑1 medications list the abdomen, the thigh and the upper arm. Tirzepatide’s labels say the arm site is the back of the upper arm, injected by another person. Most labels say to rotate the site with each dose. Max HP, a GLP‑1 dose tracker for iPhone, keeps track of which site you used and when.
The sites, in plain terms
- AbdomenThe stomach area. The Instructions for Use for Ozempic®, Zepbound® and Mounjaro® say at least 2 inches from the belly button; Wegovy®’s says the lower stomach, 2 inches away from it. Max HP splits the abdomen into four: upper and lower, left and right.
- ThighThe front of each thigh.
- Upper armThe back of each upper arm. For tirzepatide, the labels say another person gives this injection.
The Instructions for Use for your pen or vial show the exact areas in a diagram. Follow those, and ask your prescriber or pharmacist if anything is unclear.
What each label says
Quoted from the US prescribing information on DailyMed, read in November 2026. Labels change; the link goes to the current one.
| Medication | Sites | Rotation |
|---|---|---|
| Ozempic® semaglutide, weekly | “Inject OZEMPIC subcutaneously in the abdomen, thigh, or upper arm.” | No rotation instruction in the label text |
| Wegovy® semaglutide, weekly | “Inject WEGOVY subcutaneously in the abdomen, thigh, or upper arm.” | “Rotate injection sites with each dose.” |
| Zepbound® tirzepatide, weekly | “Inject ZEPBOUND subcutaneously in the abdomen, thigh, or another person should inject in the back of the upper arm.” | “Rotate injection sites with each dose.” |
| Mounjaro® tirzepatide, weekly | “Inject MOUNJARO subcutaneously in the abdomen, thigh, or have another person inject MOUNJARO in the back of the upper arm.” | “Rotate injection sites with each dose.” |
| Trulicity® dulaglutide, weekly | “Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm.” | “Rotate injection sites with each dose.” |
| Saxenda® liraglutide, daily | “Inject SAXENDA subcutaneously in the abdomen, thigh, or upper arm.” | “Rotate injection sites within the same region in order to reduce the risk of cutaneous amyloidosis” |
| Victoza® liraglutide, daily | “Inject VICTOZA subcutaneously in the abdomen, thigh or upper arm.” | “Rotate injection sites within the same region in order to reduce the risk of cutaneous amyloidosis” |
Compounded semaglutide and tirzepatide aren’t FDA-approved and have no label of this kind. Follow the instructions from your prescriber and pharmacy.
What rotating means
Rotating means not using the exact same spot dose after dose. The tirzepatide patient instructions put it this way: “You may use the same area of your body but be sure to choose a different injection site in that area.” The liraglutide labels say to rotate within the same region.
So rotating can mean moving within one area or between areas. Ask your prescriber or pharmacist which suits you. A log remembers where you went last time, so you don’t have to.
How Max HP keeps track
- A body map on every shotFront and back, with the eight sites drawn the way you see yourself.
- Days since each siteEach site shows how long since you last used it, shaded darker when it was recent.
- A suggestion, not a ruleMax HP marks the site you’ve rested longest. Tap any site to log a different one.
- Turn sites offIf your label or your prescriber rules a site out, turn it off and Max HP won’t suggest it.
- Site reactionsLog an injection-site reaction as a symptom, so it’s there to show at your appointment.
Prefer paper? The printable injection tracker has the same body map and a rotation log.
Questions
- Where can you inject a GLP‑1?
- The US labels for injectable GLP‑1 medications list the abdomen, the thigh and the upper arm. For Zepbound® and Mounjaro® (tirzepatide), the labels say the upper-arm injection is in the back of the arm, given by another person. Check the Instructions for Use for your own medication.
- Does the injection site change how the medication works?
- The labels report similar exposure across the three sites. For example, the Zepbound® label says “Similar exposure was achieved with subcutaneous administration of tirzepatide in the abdomen, thigh, or upper arm.” Ask your prescriber about your own case.
- Do I need to rotate injection sites?
- Most GLP‑1 labels say to rotate with each dose; the Wegovy®, Zepbound®, Mounjaro® and Trulicity® labels say “Rotate injection sites with each dose.” Your prescriber or pharmacist can show you how.
- What do I record if a site gets red, itchy or lumpy?
- The site, the date, what it looked like and how long it lasted. In Max HP, log it as an injection-site reaction. Tell your prescriber about reactions, and get urgent care for signs of a serious allergic reaction, such as swelling of the face or trouble breathing.
- Which side is “left” on the body map?
- Yours. The map is drawn as you see yourself looking down, so your left is on the left in both the front and the back view.
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